The low-dose monoethylglycinexylidide test: Assessment of liver function with fewer side effects
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چکیده
منابع مشابه
Effects of chronic renal failure and hemodialysis on the monoethylglycinexylidide liver function test.
the Monoethylglycinexylidide Liver Function Test, Pietro Palatini, Maura Floreani, Roberto Padrini, Pierpaolo Piccoli, Massimo Bertoli, Lorenzo Calò, and Rocco Orlando ( Department of Pharmacology and Anesthesiology and 2 Department of Medical and Surgical Sciences, University of Padova, 35131 Padova, Italy; * address correspondence to this author at: Dipartimento di Farmacologia e Anestesiolog...
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Oral contraceptive pills have several side effects especially on the gastrointestinal tract and liver. Absorption of low dose (LD) pills by the vaginal route avoids the first pass of the steroids through these tracts and probably has fewer side effects. This study was a cohort study for evaluation of side effects and acceptability of LD pills administered by the vaginal route. In a clinical...
متن کاملAssessment of monoethylglycinexylidide as measure of liver function for patients with chronic viral hepatitis.
The liver metabolizes lidocaine by oxidative deethylation to form monoethylglycinexylidide (MEGX), an analyte proposed as an index of liver function. We determined MEGX and lidocaine serum concentrations with the TDx (Abbott Laboratories) at baseline and 15, 30, 60, and 90 min after the intravenous administration of lidocaine (1 mg/kg), analyzing specimens from 12 apparently healthy volunteers ...
متن کاملValue of the in vitro or in vivo monoethylglycinexylidide test for predicting liver graft function.
BACKGROUND An adequate function test for donor livers is still lacking. The monoethylglycinexylidide (MEGX) test, performed in vivo in the donor to measure the metabolic rate of lidocaine conversion to MEGX, has been proposed as a function test for donor livers to predict postoperative organ function. METHODS In the present study, we investigated whether the MEGX formation rate measured in ne...
متن کاملIn vitro Studying of Deferasirox Side effects on the Structure and the Function of Bovine Liver Catalase
Background & Objective: Oral chelators such as deferasirox are used to treat iron overload caused by blood transfusion. Considering the significant role of liver in detoxification and drug metabolism as well as the importance of catalase as a key enzyme in detoxification, this study was performed to evaluate the effect of deferasirox, which is an iron chelator on the structure and the synt...
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ژورنال
عنوان ژورنال: Hepatology
سال: 1997
ISSN: 0270-9139,1527-3350
DOI: 10.1002/hep.510250603